The science behind calculating biological age
Chronological age tells us how many years we’ve been alive, but it doesn’t necessarily reflect our true biological condition. Biological age, in contrast, measures how old our bodies are based on physiological and molecular factors. One of the most advanced methods for calculating biological age is the PhenoAge clock, which offers a deeper insight into our overall health and potential longevity.
By James Cartwright
Phlebotomist
Understanding Biological Age and PhenoAge
Biological age assesses the functional state of our cells, tissues, and organs, influenced by genetics, lifestyle, environment, and diseases. The PhenoAge clock, developed by Dr. Morgan Levine and her team, is a sophisticated model that predicts mortality and morbidity risks better than chronological age. It uses clinical biomarkers that are readily available from standard blood tests, making it accessible and practical for widespread use.
How PhenoAge Works
PhenoAge incorporates nine biomarkers, including albumin, creatinine, glucose levels, and C-reactive protein, among others. These biomarkers are selected because they are indicative of key physiological functions such as immune response, metabolic health, and organ function. By analyzing these markers, PhenoAge calculates a biological age that reflects the cumulative effect of various health factors on the aging process.
The Significance of PhenoAge
PhenoAge is not just a number; it’s a reflection of your overall health status. A higher PhenoAge compared to your chronological age suggests accelerated aging and a higher risk of age-related diseases. Conversely, a lower PhenoAge indicates that your body is aging more slowly than average, which is associated with better health outcomes and longevity. This information empowers individuals to make informed decisions about their health and lifestyle.
Improving Your PhenoAge
Knowing your PhenoAge opens the door to targeted interventions. Lifestyle changes such as adopting a nutritious diet rich in antioxidants, engaging in regular physical activity, managing stress through mindfulness practices, and ensuring adequate sleep can positively influence your biological age. Additionally, regular monitoring allows you to track the effectiveness of these interventions over time.
Calculating your biological age using PhenoAge provides a comprehensive understanding of your health beyond the number of years you’ve lived. It highlights the areas where you can improve and motivates proactive steps toward healthier aging. Embracing this personalized approach to health can enhance your quality of life and potentially extend your lifespan.